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2.4 Experimental groups In total, 54 rats were divided into nine groups of six, including, the sham group (undergoing surgery without CCI and receiving DMSO 5%), CCI group (undergoing CCI and receiving DMSO 5%), gabapentin (positive control group, 100 mg/kg in DMSO 5%), AST-treated groups (5 and 10 mg/kg in DMSO 5%), flumazenil (FLU) (0.5 mg/kg), naloxone (NAL) (0.1 mg/kg), AST (10 mg/kg) + flumazenil (0.5 mg/kg) (AST + FLU), and AST (10 mg/kg) + naloxone (0.1 mg/kg) (AST + NAL) (Supplementary Figures 1, 2)
Meldrum, D
Foods, like cruciferous vegetables, garlic, and onions can also boost glutathione levels for better detoxification
in addition, higher circulating IGF-1 has been linked with increases in MPS, muscle free fatty acid utilization, and improvements insulin sensitivity (Kraemer et al., 1996
Another study has highlighted FK866s potential in treating neurodegenerative diseases by modulating NAD + metabolism and reducing oxidative stress to support neuronal health 220
